Pathophysiology All Unit Notes

Bachelor of Pharmacy (B.Pharma)
Pathophysiology { BP204T }
All Unit Notes in One PDF

Unit 1
Basic principles of Cell injury and Adaptation:
Introduction, definitions, Homeostasis, Components and Types of Feedback systems, Causes of cellular injury, Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage),Morphology of cell injury– Adaptive changes
(Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular accumulation, Calcification, & Alkalosis, Electrolyte imbalance
Basic mechanism involved in the process of inflammation and repair:
Introduction, Clinical signs of inflammation, Different types of Inflammation, Mechanism of Inflammation– Alteration in vascular permeability and blood flow, migration of WBC’s, Mediators of inflammation, Basic principles of wound healing in the skin, Pathophysiology of Atherosclerosis

Unit 2
Cardiovascular System:
Hypertension, congestive heart failure, ischemic heart disease (angina, myocardial infarction, atherosclerosis and arteriosclerosis)
Respiratory system : Asthma, Chronic obstructive airways diseases.
Renal system : Acute and chronic renal failure

Unit 3
Haematological Diseases:
Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, hemophilia
Endocrine system : Diabetes, thyroid diseases, disorders of sex hormones
Nervous system : Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease.
Gastrointestinal system : Peptic Ulcer

Unit 4
Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver disease.
Disease of bones and joints : Rheumatoid arthritis, osteoporosis and gout
Principles of cancer : classification, etiology and pathogenesis of cancer

Unit 5
Infectious diseases : Meningitis, Typhoid, Leprosy, Tuberculosis
Urinary tract infections
Sexually transmitted diseases : AIDS, Syphilis, Gonorrhea